of National Academy of Sciences
of Tajikistan

News of the National Academy of Sciences of Tajikistan.
Department of Biological Sciences

Известия Академии наук Республики Таджикистан. Отделение биологических и медицинских наук, №3, 2014 г.

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Niyatbekov T.P.
Ecological analysis of the diatoms (Bacillariophyta) of Pamir
There are the results of the generalization, literary analysis perennial and also original dates about ecological feature Bacillariophyta algae of the Pamir given. It is specified their dominating types and made attempt of the separation of the main ecologicl types locality of the Diatom algae (benthos, plankton, plankton-benthos and epiphyte (as component populations of algae) considered by the Pamir water bodies.

Ключевые слова: диатомовые водоросли; экология; характеристика; бентос; планктон; эпифит; Памир; Algae diatoms; ecology; analysis; benthos; plankton; epiphyte; Pamir.

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Madaminov A.A., Kalimullin A.T.
Development and productivity meadows ( community) in the highlands of Central of the Pamirо-Alay
This paper presents the results of studies of the biology and ecological features, and plant productivity forb meadows on the southern slope in the upper reaches of the river Ziddy of the Hissar range, at the height of 2840 m meadows from Ligularia heterophylla are widely distributed on Ziddy depression, their natural stock of aboveground mass averaged 2.76 t/ha fertilizer (N P ) the yield of this meadow raise up to 4.85 t/ha. Establish to change the structure of the plant under the influence of anthropogenic factors.

Ключевые слова: высокогорья Памиро-Алая; развитие, продуктивность и структура луга; Pamirо-Alai mountains; meadows; development; productivity; structure.

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Hasanov N.R., Safaraliev A.R., Mirzoev M.N., Davlatmurodov T.M.
Epizootology pnevmoenteritis of calves of the Republic of Tajikistan
Bacterial pathogens of gastrointestinal and respiratory diseases of cattle registered in all regions of the Republic of Tajikistan, which is also confirmed by the results of epizootic monitoring which have done in 18 livestock farms RT: RRS, unfavorable for infectious pnevmoenteritam were all studied farming 8 (100%) in the Khatlon region - 5 (83.3%) and Sughd - 2 (50%), in the whole of the RT, the corresponding figure was - 15 farms (83.3%)

Ключевые слова: эпизоотология; пневмоэнтериты; колибактериоз; сальмонеллёз; протеоз; пастереллёз; гастроэнтериты; пневмония; epizootology; pneumoenteritis; colibacteriosis; salmonellosis; proteos; pasteurellosis; gastroenteritis; pneumonia.

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Kadyrov A.X., Yakubova D.Sh., Dadabaev X.R.
Specific structure and distribution of bugs of Staphylinidae (Coleoptera) on biotopes
There are the vital forms for the population Staphylinidae various biotopes of the southern slope of the Hissar мountains were defined.

Ключевые слова: Таджикистан; Гиссарский хребет; жизненные формы; фауна; экология; Staphylinidae; Tajikistan; Hissar мountains; vital forms; fauna; ecology; Staphilinidae.

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Khudoydodov B.I., Razikov Sh.Sh., Rajabov U.R.
It was proveded that the ferule 10% aqueous suspension at a dose of 0.5 ml per kg body weight is almost ineffective against strongilyatosis gastrointestinal tract of sheep and gelmicid granules at a dose of 7.5 mg per kg of body weight showed a high antihelmintic efficacy against this helminthosis .

Ключевые слова: ферула; суспензия; овцы; козы; гельмицид; дегельминтизация; ferula; suspension; sheep; goats; gelmicid; deworming.

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Atoev M.H., Ergashev A., Djumaev B.B., Abdulloev A.
The potential rate of photosynthesis and photosynthetic carbon metabolism in flag leaves of kinds of wheat in the condition of chloride salinization of soil
This article concerns the impact of salt stress (0.5% NaCl) on potential rate of photosynthesis and photosynthetic carbon metabolism in flag leaves of different kinds of wheat. Under the influence of chloride salinization of soil in investigated varieties of wheat along with significant inhibition of potential rate of photosynthesis occurred qualitative and quantitative changes in insertion of assimilated of carbon tracer - C at the products of photosynthesis. The fact of more insertion of C in C -products and GPI-intermediates glycolate path under the influence of chloride salinization testifies it.

Ключевые слова: пшеница; потенциальный фотосинтез; продукты фотосинтеза; хлоридное засоление почвы; wheat; potential photosynthesis; products of photosynthesis; chloride salinization of soil.

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Numonov S.R., Yakubova M.M., Aisa H.A.
Developing the method extraction, separation, purification and quantitative analysis the total triterpenoids and their PTP-1B activities
The aim of the current study was to developing method of extraction and obtaining total triterpenoids and investigates the antidiabetic activity of getting triterpenoids and two triterpenic acids: ursolic, oleanolic acids. All compounds showed significant antidiabetic activity. The process for extracting total triterpenoids from D. heterophyllum was developed by a fairly simple and accessible method, called remaceration. This method is characterized by minimal loss of BAC on diffusion, which contributes the most complete depletion of raw materials.

Ключевые слова: PTP-1B; экстракция; выделение; очистка; тритерпеноиды; Dracocephalum heterophyllum; Dracocephalum heterophyllum; triterpenoids; PTP-1B; extraction; purification.

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Kadirov A.H., Kadirov Sh.A., Yakubova M.M.
Ursodeoxycholic acid from patients wits liver diseases
The paper presents results of studies on the effect of ursodeoxycholic acid on the nature of changes in the content of bile acids in patients with fatty liver disease, and shows the way liver a protection from harmful toxins.

Ключевые слова: жировая болезнь печени; урсодезоксихолевая кислота; газовая хроматография; желчные кислоты; fatty liver disease; ursodeoxycholic acid; gas chromatography; bile acids.

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Tabarov M.S., Kudrjashov A., Toshtemirova S.M., Shukurova N.Ja.
An andrenoreaktiviti deep - hypothermia of the body
In this work we studied the reaction of deep vein cat calf’s muscle during hypothermia of the body. Studies have shown that cooling the body led to a decrease in the reactivity of veins to the constrictor and dilatory adrenergic stimuli. Identified two critical temperature level at which there has been a sharp drop in temperature.

Ключевые слова: адренореактивность; глубокие вены; гипотермия; An Andrenoreaktivity; deep; vein; hypothermia.

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Sharofova M., Nuraliev Y.N., Zaher M., Marie J-P., Billard C., Sagdieva Sh.S., Mirshahi M.
The new plant-derived extract M2Yn induced apoptosis of chronic lymphocytic leukemia cells by activation of the BH3-only protein Noxa
M2Yn is new antiangiogenic natural extract blocking the migration of malignant cells. It has been shown that treatment of cells from patients with chronic lymphocytic leukemia (CLL) in vitro by drug M2Yn leads to intranuclear DNA fragmentation, externalization of phosphatidylserine, can activate proteasome inhibitors, causes depolarization of mitochondrial membranes, caspase-3 activation and cleavage of caspase substrate PARP-1. The degree of manifestation of these effects depends on the patients, and generally comparable with flavopiridol or hyperforin, two known inducers of apoptosis of CLL cells of plant origin. Confirmed also that the BH3-only protein Noxa is a suitable target for the treatment of CLL.

Ключевые слова: M2Yn; апоптоз; хронический лимфолейкоз; BH3-единичный белок Noxa; семейство Bcl-2; M2Yn; apoptosis; chronic lymphocytic leukemia; BH3-only protein Noxa; Всl-2 family.

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Khamidov N.Kh., Khursanov N.M., Saidmurodova F.L.
Melatonin in the treatment of diseases of the cardiovascular system
The article presents an update data on melatonin and its role in ensuring of normal functioning of the human body. The data on the effect of melatonin on the cardiovascular system as well as its role in the pathogenesis of depression, sleep disorders, metabolic syndrome, coronary heart disease and hypertension are also given. The problems of the synthesis of endogenous melatonin and the effect of its hormone on a daily and seasonal adjustment of the human body, particularly in the elderly, are considered.

Ключевые слова: эпифиз; мелатонин; качество жизни; комбинированная терапия; пожилой возраст; epiphysis; melatonin; quality of life; combination therapy; old age.

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Shokirov Yu.A., Chuklina E.O., Dzhalilov S.S., Babahkodjaeva Z.B.
Some clinical features of chronic kidney disease with diffuse glomerulonephritis
Examination of 96 patients with chronic renal failure, which developed in the basis of diffuse glomerulonephritis conducted to establish early detection and clinical features of symptomatology. Clinical observations have shown that the most frequently observed arterial hypertension (77.0%), edema moderately expressed and absent in 39.6%, high proteinuria observed in 38.5% of patients. With increasing stage of CKD, especially in ESRD, increases the frequency and severity of hypertension, is progressively reduced GFR increases the content of toxic nitrogenous wastes in the blood worsens survival. Early detection and establishing the nature and severity of symptomatology CRF allow for a timely comprehensive nephrotoxicity cardioprotective treatment

Ключевые слова: хроническая болезнь почек; хроническая почечная недостаточность; хронический гломерулонефрит; артериальная гипертония; chronic kidney disease (CKD); chronic renal failure (CRF); chronic glomerulonephritis (CGN); arterial hypertension (AH).

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Abduvokhidov A.A., Solikhov D.N.
The efectiveness of tamsulozin in patients with chronic abacterial prostatitis
Using international scale of IPSS, QoL and NIH-CPSI (USA) we are identified and assessed management of chronic abacterial prostatitis with tamsulozin. All patients underwent anti-inflammatory and symptomatic therapy for 2 weeks. Of these patients, 50 patients took alpha -1 -blocker (tamsulosin at 0.4 mg/day), except for anti-inflammatory and symptomatic therapy, for 3 months. We assessed the quality of life of these patients every month for 3 months, in the background and after treatment. As a result, it revealed improvement of quality of life in patients with chronic abacterial prostatitis, by alpha -1 -blocker (tamsulosin) therapy.

Ключевые слова: хронический абактериальный простатит; оценка качества жизни; тамсулозин; chronic abacterial prostatitis; evaluation quality of life; tamsulosin.

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